Please read the information linked below. It contains important warnings from the FDA in relation to medications you may be prescribed. If you have any questions, please speak to your provider or other licensed healthcare professional.
Medication Information
Compounded liraglutide
*Compounded medications may be prescribed by physicians but have not been FDA regulated for safety, effectiveness, or quality. FDA-approved medicines containing semaglutide are available.
Potential Drug Interactions
- Patients should consult their provider before using multiple GLP-1 medications (e.g., Ozempic®, Wegovy®, Rybelsus®).
- Patients using insulin or sulfonylureas should speak with their provider about potential adjustments to avoid low blood sugar.
- Certain medications may interact with GLP-1 receptor agonists—patients should consult their provider or pharmacist regarding possible interactions.
Important Safety Information
Take as directed by a licensed provider. Patients should follow their licensed healthcare provider’s instructions regarding treatment and administration.
Most common side effects:
- Nausea
- Stomach (abdominal) pain
- Diarrhea
- Vomiting
- Decreased appetite
- Constipation
Serious Risks:
- Thyroid Tumors & Cancer: Some FDA-approved GLP-1 medications include a boxed warning related to thyroid tumors observed in animal studies.
- Pancreatitis Risk: Patients should contact their provider if they experience severe abdominal pain.
- Kidney Function: Dehydration may contribute to kidney issues in certain individuals.
Certain medical conditions may impact whether GLP-1 medications are a safe and appropriate option. Patients should consult their healthcare provider to determine eligibility based on their medical history.
Not recommended for individuals with:
- Personal or family history of medullary thyroid carcinoma (MTC)
- Multiple endocrine neoplasia syndrome type 2 (MEN2)
- History of pancreatitis
- Severe kidney disease
- Diabetic ketoacidosis
- Type 1 diabetes
Use with caution in individuals with:
- Diabetic retinopathy (consult a healthcare provider for personalized guidance)
A medical evaluation is essential to ensure safe and effective treatment. Always discuss your health history with your provider before starting any new medication.
For a full list of side effects view here: [Mayo Clinic]
Pregnancy & Breastfeeding
- Patients who are pregnant, breastfeeding, or planning to conceive should consult their healthcare provider to determine if treatment is appropriate.
- Patients should discontinue at least 2 months before planning pregnancy.
Storage
- Store refrigerated.
- Avoid exposure to direct sunlight and moisture.
Higher Dose Needed?
- Patients should consult their healthcare provider if they have questions about their dosing or treatment options..
MIC+B12
Safety Information:
Side effects are typically mild and go away over time.
Common side effects:
- Discomfort or redness at the injection area
- Skin itching or sensations of overall swelling
- Muscular cramps and weakness
- Nausea and issues with urination
- Swelling around the ankles or feet
- Excessive fatigue
Precautions:
- Avoid using MIC+B12 if you are pregnant, nursing, or if you are planning to become pregnant or to breastfeed.
- Should itching/irritation persist, consider using an over-the-counter anti-itch cream containing hydrocortisone, or stop using the product altogether.
- In the uncommon event of more severe reactions, such as an irregular heartbeat or difficulty breathing, cease usage immediately and consult your healthcare provider.
Note: The statements above have not been reviewed by the Food and Drug Administration. This product is not designed to diagnose, treat, cure, or prevent any condition.
Safety Information: Compounded Semaglutide
Regulatory Disclosure
Compounded semaglutide is not FDA-approved. While it contains semaglutide, active ingredient found in FDA-approved medications like Wegovy® and Ozempic®, compounded semaglutide is prepared by a licensed compounding pharmacy under the provisions of Section 503A of the Federal Food, Drug, and Cosmetic Act. These medications are compounded specifically for individual patients and are only dispensed when deemed medically necessary by a licensed provider.
Disclaimer: The FDA does not review or approve compounded medications for safety, effectiveness, or quality. However, compounding pharmacies that prepare these formulations must follow strict state regulations and standards enforced by their respective state boards of pharmacy.
Prescribing & Eligibility
In accordance with FDA guidelines, you must be medically qualified by a licensed provider before receiving a prescription for any medication, including compounded drugs. A compounded medication may only be prescribed if your provider determines:
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You have a valid medical condition that warrants treatment.
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A commercially available FDA-approved alternative (such as Wegovy® or Ozempic®) is not medically appropriate or accessible for you.
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The benefits of compounded treatment outweigh the risks for your individual case.
Prescriptions will only be issued after a complete clinical review of your intake forms, medical history, and eligibility.
Risks & Side Effects
As with all medications containing semaglutide, patients may experience the following common side effects:
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Nausea
-
Vomiting
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Diarrhea
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Constipation
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Abdominal discomfort
-
Decreased appetite
Serious risks may include:
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Pancreatitis
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Gallbladder disease
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Gastroparesis (delayed stomach emptying)
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Acute kidney injury
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Hypoglycemia (low blood sugar), especially when used with other diabetes medications
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Risk of thyroid C-cell tumors (including medullary thyroid carcinoma)
Contraindications
Do not take semaglutide if:
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You are pregnant, trying to become pregnant, or breastfeeding
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You have a personal or family history of medullary thyroid carcinoma (MTC)
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You have Multiple Endocrine Neoplasia Syndrome type 2 (MEN 2)
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You have a known hypersensitivity to semaglutide or any ingredient in the formulation
If pregnancy occurs, you must immediately notify your provider and stop treatment. Semaglutide should be discontinued at least 2 months prior to any planned pregnancy due to potential risks to the fetus.
Informed Consent & Monitoring
By initiating treatment with compounded semaglutide:
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You acknowledge that you understand this is not an FDA-approved drug product.
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You consent to regular follow-ups with your provider to monitor response, side effects, and dose adjustments.
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You agree to use an effective form of birth control during treatment if of childbearing potential.
Adverse Event Reporting
If you experience a side effect or unexpected reaction, contact your provider immediately. You may also report side effects to the FDA MedWatch Program at www.fda.gov/medwatch or call 1-800-FDA-1088.
Additional Information
Compounded semaglutide is dispensed through FDA-registered 503A compounding pharmacies that follow all federal and state compounding regulations. Your prescription is tailored to your individual needs and may differ in concentration, dosage form, or delivery method compared to FDA-approved medications.