Semaglutide has side effects, as do all medications. It is generally well-tolerated.
The most common side-effects reported in clinical trials are:
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach pain
- Headache
- Fatigue
- Upset stomach
- Dizziness
- Feeling bloated
- Belching
- Stomach flu
- Heartburn
More serious side-effects include:
- Inflammation of the pancreas
- Potential increased risk of thyroid C-cell tumors
- Gallbladder problems
- Low blood sugar
- Kidney problems
- Serious allergic reactions
- Increased heart rate
- Depression or thoughts of suicide
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